GHRH/GH-Axis
CJC-1295 No DAC Research Peptide
CJC-1295 No DAC (also known as Mod GRF 1-29) is the non-conjugated form of CJC-1295. Without the Drug Affinity Complex linker, it has a much shorter half-life, research uses it to study sharper, more pulsatile GHRH receptor activation patterns versus the extended profile of CJC-1295 with DAC.
$54.99 — 5mg vial
| Purity | ≥99% |
| Quantity | 5mg |
| Molecular Weight | 3367.97 g/mol |
| Sequence | Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH₂ |
| Category | GHRH/GH-Axis |
| Latest batch tested | 06/19/26 |
CJC-1295 No DAC in Research
CJC-1295 No DAC — also catalogued in the literature as Mod GRF 1-29 — is the unconjugated form of the CJC-1295 GHRH analog. Without the albumin-binding linker its half-life is short, producing the pulsatile receptor activation profile that more closely mirrors endogenous GHRH release in animal models.
Supplied lyophilized at 5mg and ≥99% HPLC purity, independently verified per batch. It is the standard comparator to the DAC-conjugated version, and is frequently studied alongside the ghrelin-receptor agonist Ipamorelin in dual-pathway secretagogue research.
Research Overview
- Investigated for short-acting GHRH receptor activation
- Studied for pulsatile GH release that more closely mimics endogenous patterns
- Research into combined administration with GH secretagogues (e.g. ipamorelin)
- Preclinical pharmacokinetic comparisons against DAC-conjugated CJC-1295
- Explored for GH/IGF-1 axis modulation without sustained receptor saturation
Quality & Testing
Every CJC-1295 No DAC batch is verified by independent third-party HPLC and mass-spectrometry testing, with a batch-specific certificate of analysis available on the COA page.
Laboratory Handling & Storage
Lyophilized peptides are supplied as a freeze-dried powder and are most stable stored cold (2–8°C), protected from light and moisture, in the original sealed vial. Under these conditions the research literature generally reports multi-year integrity for dry peptide material.
Once reconstituted in a laboratory setting, solutions are typically stored refrigerated and used within the window appropriate to the diluent and compound; repeated freeze–thaw cycles are avoided because they can promote aggregation. See our research overview on reconstitution and lyophilization for the underlying formulation science.
Frequently Asked Questions
Is CJC-1295 No DAC the same as Mod GRF 1-29?
Yes — the two names refer to the same tetrasubstituted GHRH(1-29) analog. 'No DAC' distinguishes it from the albumin-conjugated long-acting version.
Why pair it with Ipamorelin in research?
They act on complementary receptors: this compound on the GHRH receptor and Ipamorelin on the ghrelin receptor (GHS-R1a). Dual-pathway designs use the pair to study additive secretagogue signaling in models.
Is CJC-1295 No DAC for human use?
No. It is supplied strictly for laboratory research and is not for human consumption or any medical application.