Short-Chain Peptides
KPV Research Peptide
KPV is a tripeptide derived from the C-terminal fragment of alpha-melanocyte-stimulating hormone (α-MSH). It has been studied for its potent anti-inflammatory properties mediated through NF-κB pathway inhibition.
$54.99 — 10mg vial
| Purity | ≥99% |
| Quantity | 10mg |
| Molecular Weight | 342.43 g/mol |
| Sequence | Lys-Pro-Val |
| Category | Short-Chain Peptides |
| Latest batch tested | 06/19/26 |
KPV in Research
KPV is the C-terminal tripeptide fragment (Lys-Pro-Val) of alpha-melanocyte-stimulating hormone, studied for anti-inflammatory signaling that operates independently of the classical melanocortin receptors — most notably inhibition of NF-κB pathway activation and downstream pro-inflammatory cytokine production in cell models.
At 342.43 g/mol, KPV is the smallest peptide in our catalog. Supplied lyophilized at 10mg and ≥99% purity with independent batch verification, it also features as a component of the KLOW research blend.
Research Overview
- Investigated for NF-κB signaling pathway inhibition and anti-inflammatory effects
- Studied for modulation of pro-inflammatory cytokine production in cell models
- Research into intestinal inflammation reduction in preclinical colitis models
- Explored for wound healing acceleration via anti-inflammatory mechanisms
- Preclinical studies on antimicrobial properties against intracellular pathogens
Quality & Testing
Every KPV batch is verified by independent third-party HPLC and mass-spectrometry testing, with a batch-specific certificate of analysis available on the COA page.
Laboratory Handling & Storage
Lyophilized peptides are supplied as a freeze-dried powder and are most stable stored cold (2–8°C), protected from light and moisture, in the original sealed vial. Under these conditions the research literature generally reports multi-year integrity for dry peptide material.
Once reconstituted in a laboratory setting, solutions are typically stored refrigerated and used within the window appropriate to the diluent and compound; repeated freeze–thaw cycles are avoided because they can promote aggregation. See our research overview on reconstitution and lyophilization for the underlying formulation science.
Frequently Asked Questions
What is KPV?
KPV is the Lys-Pro-Val tripeptide fragment of α-MSH, studied in laboratory models for NF-κB pathway inhibition and modulation of inflammatory cytokine production.
How does KPV relate to the melanotan compounds?
All derive from α-MSH, but differently: the melanotans are receptor-agonist analogs of the full hormone, while KPV is the C-terminal fragment studied for receptor-independent anti-inflammatory signaling.
Is KPV for human use?
No. KPV is a laboratory research compound only — not for human consumption, diagnosis, or treatment.