Melanocortin Peptides
Melanotan I Research Peptide
Melanotan I (afamelanotide) is a linear 13-amino-acid analog of alpha-melanocyte stimulating hormone (α-MSH) with selective affinity for the MC1R receptor. Supplied lyophilized as a laboratory reference compound. For research use only.
$39.99 — 10mg vial
| Purity | ≥99% |
| Quantity | 10mg |
| Molecular Weight | 1646.85 g/mol |
| Sequence | Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH₂ |
| Category | Melanocortin Peptides |
Melanotan I in Research
Melanotan I is a linear 13-amino-acid analog of alpha-melanocyte-stimulating hormone with selective affinity for the melanocortin-1 receptor (MC1R). In the research literature it serves as the selective counterpart to broader-spectrum analogs, making it a staple of receptor-pharmacology and eumelanin-synthesis studies.
Aurum supplies Melanotan I lyophilized at 10mg per vial, ≥99% chromatographic purity, with independent HPLC and mass-spectrometry verification documented per batch.
Research Overview
- Studied for selective MC1R agonist signaling relative to broader melanocortin analogs
- Investigated for eumelanin synthesis and melanogenesis pathway activation
- Research into photoprotective endpoints in preclinical models
- Explored for extended plasma half-life versus native α-MSH
- Preclinical profiling of receptor binding selectivity and molecular stability
Quality & Testing
Every Melanotan I batch is verified by independent third-party HPLC and mass-spectrometry testing, with a batch-specific certificate of analysis available on the COA page.
Laboratory Handling & Storage
Lyophilized peptides are supplied as a freeze-dried powder and are most stable stored cold (2–8°C), protected from light and moisture, in the original sealed vial. Under these conditions the research literature generally reports multi-year integrity for dry peptide material.
Once reconstituted in a laboratory setting, solutions are typically stored refrigerated and used within the window appropriate to the diluent and compound; repeated freeze–thaw cycles are avoided because they can promote aggregation. See our research overview on reconstitution and lyophilization for the underlying formulation science.
Frequently Asked Questions
What is Melanotan I?
Melanotan I is a linear synthetic α-MSH analog studied for selective MC1R agonism and melanogenesis-pathway signaling in laboratory models.
Why choose Melanotan I over Melanotan II for receptor studies?
Its selectivity. The linear analog favors MC1R, whereas the cyclic Melanotan II engages multiple melanocortin receptor subtypes — so the pair together allows selectivity-controlled experimental designs.
Is Melanotan I for human use?
No. This is a laboratory reference compound for research use only — not for human consumption, diagnosis, or treatment.