Neuropeptides
Semax Research Peptide
Semax is a synthetic peptide analog of a fragment of adrenocorticotropic hormone (ACTH 4-10). It has been the subject of neurochemistry research for its potential cognitive effects.
$44.99 — 5mg vial
| Purity | ≥99% |
| Quantity | 5mg |
| Molecular Weight | 813.93 g/mol |
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
| Category | Neuropeptides |
| Latest batch tested | 06/19/26 |
Semax in Research
Semax is a synthetic heptapeptide analog of the ACTH(4-10) fragment, studied extensively in neurochemistry research for modulation of BDNF and NGF expression and for neuroprotective mechanisms in ischemia models. Like Selank, it originates from the Russian regulatory-peptide research tradition.
Supplied lyophilized at 5mg per vial and ≥99% HPLC purity, with independent identity and purity verification documented on each batch's certificate of analysis.
Research Overview
- Investigated for BDNF and NGF modulation in neural tissue
- Studied for neuroprotective mechanisms in ischemia models
- Research into dopaminergic and serotonergic system interactions
- Explored for cognitive enhancement in animal behavioral tests
- Preclinical research on attention and memory processes
Quality & Testing
Every Semax batch is verified by independent third-party HPLC and mass-spectrometry testing, with a batch-specific certificate of analysis available on the COA page.
Laboratory Handling & Storage
Lyophilized peptides are supplied as a freeze-dried powder and are most stable stored cold (2–8°C), protected from light and moisture, in the original sealed vial. Under these conditions the research literature generally reports multi-year integrity for dry peptide material.
Once reconstituted in a laboratory setting, solutions are typically stored refrigerated and used within the window appropriate to the diluent and compound; repeated freeze–thaw cycles are avoided because they can promote aggregation. See our research overview on reconstitution and lyophilization for the underlying formulation science.
Frequently Asked Questions
What is Semax?
Semax is a synthetic analog of the ACTH(4-10) fragment (Met-Glu-His-Phe-Pro-Gly-Pro) studied in preclinical models for neurotrophin modulation — notably BDNF and NGF — and neuroprotective signaling.
What distinguishes Semax from Selank in research designs?
Different parent molecules and different signaling profiles: Semax derives from an ACTH fragment and is studied around neurotrophin expression, while Selank derives from tuftsin with a more immunomodulatory literature. Together they form a common comparator pair.
Is Semax for human use?
No. Semax is a research compound for laboratory use only. It is not FDA-approved and is not for human consumption.