Short-Chain Peptides
SS-31 Research Peptide
SS-31 (elamipretide) is a mitochondria-targeted tetrapeptide with a cell-permeable aromatic-cationic motif that associates with cardiolipin on the inner mitochondrial membrane. Supplied lyophilized as a laboratory reference compound. For research use only.
$65.99 — 10mg vial
| Purity | ≥99% |
| Quantity | 10mg |
| Molecular Weight | 639.80 g/mol |
| Sequence | D-Arg-Dmt-Lys-Phe-NH₂ |
| Category | Short-Chain Peptides |
| Latest batch tested | 08/14/26 |
SS-31 in Research
SS-31 (elamipretide) is a mitochondria-targeted tetrapeptide whose aromatic-cationic motif concentrates it at the inner mitochondrial membrane, where it associates with cardiolipin. The research literature examines electron-transport-chain efficiency, cristae-structure stabilization, and oxidative-stress endpoints in preclinical models — making it a cornerstone compound of mitochondrial pharmacology.
Supplied lyophilized at 10mg and ≥99% purity, independently verified per batch with published COA documentation.
Research Overview
- Studied for selective binding to cardiolipin on the inner mitochondrial membrane
- Investigated for effects on electron transport chain efficiency in preclinical models
- Research into reactive oxygen species generation and mitochondrial redox balance
- Explored for cristae architecture and mitochondrial morphology in cell models
- Preclinical studies on bioenergetic output in cardiac and skeletal muscle tissue
Quality & Testing
Every SS-31 batch is verified by independent third-party HPLC and mass-spectrometry testing, with a batch-specific certificate of analysis available on the COA page.
Laboratory Handling & Storage
Lyophilized peptides are supplied as a freeze-dried powder and are most stable stored cold (2–8°C), protected from light and moisture, in the original sealed vial. Under these conditions the research literature generally reports multi-year integrity for dry peptide material.
Once reconstituted in a laboratory setting, solutions are typically stored refrigerated and used within the window appropriate to the diluent and compound; repeated freeze–thaw cycles are avoided because they can promote aggregation. See our research overview on reconstitution and lyophilization for the underlying formulation science.
Frequently Asked Questions
What is SS-31?
SS-31 is a synthetic tetrapeptide (D-Arg-Dmt-Lys-Phe-NH₂) studied for selective cardiolipin binding at the inner mitochondrial membrane and downstream effects on electron-transport efficiency in models.
How does SS-31 differ from MOTS-c in mitochondrial research?
SS-31 is a synthetic membrane-targeting peptide acting at cardiolipin, while MOTS-c is encoded by the mitochondrial genome itself and studied as a metabolic signaling peptide. They probe different arms of mitochondrial biology and are often used together as complementary tools.
Is SS-31 for human use?
No. SS-31 is supplied strictly for laboratory research — not an approved therapeutic and not for human administration.